This picture was made with multiple mediums.
For the latex facemask, the negative was molded in clay so the latex could be smeared on in layers and give the mask gradual thinning towards the edges. When it was taken out of the negative a thin slit was cut in the mouth indent, for air, and then it was painted and stuck on models face. The background was made in 3Ds Max and then later added to the photo using Photoshop. The model was shot in front of a green screen.